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Women’s Center for Mind-Body Health
Hospital Research (Intraop) |
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The focus of this research database is on how stress affects women's health, and options for treatment using mind-body therapies. To obtain full summaries of the articles, see "How to Get Abstracts" below .
Intraop
[In general, intraoperative medical suggestions have mixed results, whereas preoperative suggestions are more consistently successful.]
Imagery - Positive Effects
11594100 RCT Assessment of the effects of a taped cognitive behavior message on postoperative complications (therapeutic suggestions under anesthesia) Patients having bariatric surgery who were played a tape of therapeutic suggestions in the OR and immediately following surgery, were able to function easier and left the hospital 1.6 days earlier. 2001 Obes Surg 11;5:589-93 Cowan, G. S. Jr, Buffington, C. K., Cowan, G. S. 3rd, and Hathaway, D.
11472279 RCT Improved recovery after music and therapeutic suggestions during general anaesthesia: a double-blind randomised controlled trial Intraoperative suggestions to hysterectomy patients under general anesthesia led to less immediate pain medication use and less fatigue. 2001 Acta Anaesthesiol Scand 45;7:812-7 Nilsson, U., Rawal, N., Unestahl, L. E., Zetterberg, C., and Unosson, M.
10562780 RCT Intraoperative therapeutic suggestions in day-case surgery: are there benefits for postoperative outcome? Patients having hernia repair under general anesthesia who were played a suggestion tape in the OR had significantly less nausea in the immediate postop hour and less headaches and muscle aches overall, but no change in pain or medication use. 1999 Br J Anaesth 82;6:861-6 Lebovits, A. H., Twersky, R., and McEwan, B.
9699102 RCT Therapeutic suggestions given during neurolept-anaesthesia decrease post-operative nausea and vomiting Double blind German study of 100 thyroidectomy patients, who either listened to positive taped suggestions or a blank tape while under general anesthesia. Suggestion patients had significantly less postop nausea and vomiting, and required less anti-emetic rx. 1998 Eur J Anaesthesiol 15;4:446-52 Eberhart, L. H., Doring, H. J., Holzrichter, P., Roscher, R., and Seeling, W.
8179147 RCT The incidence and severity of postoperative nausea and vomiting in patients exposed to positive intra-operative suggestions Double blind study of intraop suggestions to gyn surgery patients. Those who received the suggestions had significantly less nausea and vomiting in the 24 hours after surgery. 1994 Anaesthesia 49;4:340-2 Williams, A. R., Hind, M., Sweeney, B. P., and Fisher, R.
2900410 RCT Improved recovery and reduced postoperative stay after therapeutic suggestions during general anaesthesia Double-blind trial of women undergoing hysterectomy under general anesthesia who listened to a suggestion tape in the OR had significantly shorter hospital stays and less bowel problems. Interestingly, 18/19 suggestion tape patients correctly guessed they had listened to suggestions. 1988 Lancet 2;8609:491-3 Evans, C. and Richardson, P. H.
2224266 RCT Postoperative analgesic requirements in patients exposed to positive intraoperative suggestions Double blind trial showed significantly less pain medication use in hysterectomy patients under general anesthesia who listened to a suggestion tape in the OR, although pain scores were the same. 1990 BMJ 301;6755:788-90 McLintock, T. T., Aitken, H., Downie, C. F., and Kenny, G. N.
Imagery - Neutral Results
1952199 RCT Efficacy of therapeutic suggestions for improved postoperative recovery presented during general anesthesia Double blind study of major surgery patients who were played a tape of postop suggestions in the OR. No therapeutic effects were shown. [Important to evaluate in all of these studies just how the suggestions were worded. This study suggested "a short postoperative stay without pain, nausea, or vomiting". There are better ways to say this, plus it is better to tell patients that they will be able to cope with symptoms rather than that there will be none.] 1991 Anesthesiology 75;5:746-55 Block, R. I., Ghoneim, M. M., Sum Ping, S. T., and Ali, M. A.
8712392 RCT Therapeutic suggestion has no effect on postoperative morphine requirements Gynecologic surgery patients under general anesthesia did not show any effect of intraoperative suggestions to decrease pain, anxiety or nausea. The patients, however, remembered a story they were played. 1996 Anesth Analg 82;1:148-52 van der Laan, W. H., van Leeuwen, B. L., Sebel, P. S., Winograd, E., Baumann, P., and Bonke, B.
11167439 RCT Patient-controlled analgesia and intra-operative suggestion Double-blind study showing patients under general anesthesia who were played a positive suggestion tape in the OR did not show any benefit. 2001 Anaesthesia 56;1:65-9 Dawson, P., Van Hamel, C., Wilkinson, D., Warwick, P., and O'Connor, M.
1547052 RCT Therapeutic suggestions during general anaesthesia in patients undergoing hysterectomy Double-blind study of hysterectomy patients under general anesthesia did not show any improvement in outcome by listening to a suggestion tape in the OR. 1992 Br J Anaesth 68;3:277-81 Liu, W. H., Standen, P. J., and Aitkenhead, A. R.
Music
11574356 RCT Music decreases sedative requirements during spinal anesthesia Patients using spinal anesthesia who listened to music during the perioperative period required less sedative medication during surgery. 2001 Anesth Analg 93;4:912-6 Lepage, C., Drolet, P., Girard, M., Grenier, Y., and DeGagne, R.
2229703 JA Patients' perceptions of music during surgery When interviewed the next day, 90% of patients who listened to music during their non-general anesthetic surgery felt in had helped in a good to excellent manner to decrease anxiety, act as a distractor and decrease pain threshold. 1990 J Adv Nurs 15;9:1045-51 Stevens, K.
8548216 E Music in the operating theatre Editorial on the positive effects of music in the OR on patients and physicians. 1995 Br J Surg 82;12:1586-7 Thompson, J. F. and Kam, P. C.
7811324 CT Effects of music on cardiovascular reactivity among surgeons Self-selected (music loving) surgeons in a stressful lab setting showed decreased autonomic reactivity and improved performance when they listened to music of their own choice. 1994 JAMA 272;11:882-4 Allen, K. and Blascovich, J.
3761226 JA Heart rate as an indicator of stress in surgeons and anaesthetists Surgeon's heart rates in the OR were higher than anesthesiologists, and this increase began when they started scrubbing up. 1986 J Psychosom Res 30;4:411-20 Payne, R. L. and Rick, J. T.
Physiology
9738698 JA Low T3 syndrome with asynchronous changes of TT3 and rT3 values in laparoscopic cholecystectomy Laparoscopic cholecystectomy patients showed normal levels of TSH and T4 before, during and after surgery. However, T3 levels dropped early during induction of anaesthesia, remained low and dropped further 24 hours postop, the limits of this study. 1998 Endocr Res 24;2:205-13 Legakis, I. N., Golematis, B. C., Dourakis, N., Lymberopoulou, I., Mountokalakis, T., and Leandros, E. A.
8333794 R,T Comparative pharmacology of the thyroid hormones Surgical conditions can interfere with thyroid hormone metabolism, leading to low T3 syndrome. 1993 Ann Thorac Surg 56;1 Suppl:S2-6; discussion S6-8 Sypniewski, E.
7478085 R,T [Effect of menstrual cycle on the immune response to surgical stress] [Article in Italian] Per abstract, women operated on during the perimenopausal phase of the menstrual cycle had significant decreases in CD4 and C3 cell activity. 1995 Minerva Ginecol 47;5:197-205 Lazzaretti, M. G., Zenezini Chiozzi, A., Bernardelli, D., Castellani Tarabini, C., Gavioli, M., Piccagli, I., Rosi, A., Biagini, M., and Romani, M.
8341173 JA Response of ovary in young women experiencing laparoscopy under general anaesthesia Women undergoing laparoscopy under general anesthesia had significant intraoperative elevations of estradiol and testosterone, but not progesterone. 1993 Med J Malaysia 48;1:56-63 Chow, W. P., Loganath, A., Peh, K. L., Chew, P. C., Gunasegaram, R., and Ratnam, S. S.
6218673 JA Serum levels of cortisol, dehydroepiandrosterone, dehydroepiandrosterone sulphate, estrone and prolactin after surgical trauma in postmenopausal women Besides elevations in cortisol and prolactin in response to surgical stress, there was a significant increase in estrone levels in postmenopausal women. 1982 Ups J Med Sci 87;3:201-13 Adami, H. O., Axelsson, O., Carlstrom, K., Vegelius, J., and Akerstrom, G.
9633017 JA Persistent endocrine stress response in patients undergoing cardiac surgery Significant elevations of cortisol, growth hormone and norepinephrine persist for more than two days after surgery. 1998 J Endocrinol Invest 21;1:12-9 Roth-Isigkeit, A., Brechmann, J., Dibbelt, L., Sievers, H. H., Raasch, W., and Schmucker, P.
2546852 JA Beta-endorphin and ACTH levels in the perioperative period In groups premedicated or not, arrival in the OR led to an increase in beta-endorphin but not ACTH, whereas one hour postop the beta-endorphin level was even higher while ACTH levels had increased. 1989 Gen Pharmacol 20;4:399-402 Marschall, K., Schlesinger, M. D., Turndorf, H., and Puig, M. M.
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